During glycolysis, one molecule of is broken down into two molecules of pyruvate, driving the synthesis of atp.


Question: During glycolysis, one molecule of is broken down into two molecules of pyruvate, driving the synthesis of atp.

Correct. During glycolysis, one molecule of glucose (C6H12O6) is broken down into two molecules of pyruvate (C3H4O3), driving the synthesis of two molecules of ATP.

Glycolysis is the first stage of cellular respiration, and it can occur in the absence of oxygen. It occurs in the cytoplasm of the cell, and it produces a net gain of two ATP molecules per molecule of glucose.

The steps of glycolysis are as follows:

  1. Glucose is phosphorylated to form glucose-6-phosphate.
  2. Glucose-6-phosphate is rearranged to form fructose-6-phosphate.
  3. Fructose-6-phosphate is phosphorylated to form fructose-1,6-bisphosphate.
  4. Fructose-1,6-bisphosphate is split into two three-carbon molecules: dihydroxyacetone phosphate (DHAP) and glyceraldehyde 3-phosphate (G3P).
  5. DHAP is converted to G3P.
  6. G3P is oxidized to 1,3-bisphosphoglycerate (1,3-BPG), with the production of NADH.
  7. 1,3-BPG is phosphorylated to form 3-phosphoglycerate (3-PG), with the production of ATP.
  8. 3-PG is rearranged to form 2-phosphoglycerate (2-PG).
  9. 2-PG is dephosphorylated to form phosphoenolpyruvate (PEP), with the production of ATP.
  10. PEP is decarboxylated to form pyruvate.

The two pyruvate molecules produced by glycolysis can then enter the Krebs cycle and oxidative phosphorylation to produce more ATP.

Therefore, the statement "During glycolysis, one molecule of glucose is broken down into two molecules of pyruvate, driving the synthesis of ATP" is correct.

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