Describe the pathophysiology of one disorder that affects the normal metabolism of a macronutrient.

Question: Describe the pathophysiology of one disorder that affects the normal metabolism of a macronutrient.

One disorder that affects the normal metabolism of a macronutrient is metabolic syndrome. Metabolic syndrome is a cluster of conditions that increase the risk of heart disease, stroke, and diabetes. These conditions include high blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol or triglyceride levels. Metabolic syndrome is closely linked to overweight or obesity and inactivity. It's also linked to a condition called insulin resistance. Normally, your digestive system breaks down the foods you eat into sugar. Insulin is a hormone made by your pancreas that helps sugar enter your cells to be used as fuel. In people with insulin resistance, cells don't respond normally to insulin, and glucose can't enter the cells as easily. As a result, glucose levels in your blood rise despite your body's attempt to control the glucose by churning out more and more insulin. The excess glucose is stored as fat, which can lead to weight gain and other health problems.

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