In the blood clotting cascade mechanism, which specific enzyme catalyzes the conversion of fibrinogen to fibrin?
Question: In the blood clotting cascade mechanism, which specific enzyme catalyzes the conversion of fibrinogen to fibrin?
The blood clotting cascade is a complex process that involves the activation of various factors and enzymes in response to an injury. One of the final steps of this process is the conversion of fibrinogen, a soluble plasma protein, to fibrin, an insoluble mesh that forms the basis of the clot. The enzyme that catalyzes this reaction is called thrombin, which is generated from its inactive precursor prothrombin by another enzyme called factor Xa. Thrombin not only converts fibrinogen to fibrin, but also activates other factors that stabilize and regulate the clot formation.
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