What property prevents the ligands of cell-surface receptors from entering the cell?
Thursday, February 29, 2024
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Question: What property prevents the ligands of cell-surface receptors from entering the cell?
One of the main characteristics of cell-surface receptors is that they bind to ligands that are unable to cross the plasma membrane. These ligands are usually water-soluble molecules, such as hormones, neurotransmitters, or growth factors, that need to transmit a signal from the extracellular environment to the intracellular space. The property that prevents the ligands of cell-surface receptors from entering the cell is that they are hydrophilic and cannot penetrate the hydrophobic interior of the plasma membrane. Instead, they bind to the receptors on the cell surface, triggering a signaling cascade and the release of secondary messengers.
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