Which of the following types of metabolic poison would most directly interfere with glycolysis?


Question: Which of the following types of metabolic poison would most directly interfere with glycolysis?

The type of metabolic poison that would most directly interfere with glycolysis is an agent that binds to pyruvate and inactivates it.

Glycolysis is the first step in cellular respiration, and it results in the conversion of glucose to pyruvate. Pyruvate is then used to produce ATP, the cell's energy currency, in the citric acid cycle and oxidative phosphorylation.

If an agent binds to pyruvate and inactivates it, it will prevent pyruvate from entering the citric acid cycle and oxidative phosphorylation. This will stop the production of ATP, and the cell will die.

Here are some examples of agents that bind to pyruvate and inactivate it:

  • Arsenic
  • Cyanide
  • Fluoride
  • Iodoacetate
  • Oxalate

These agents can be found in a variety of sources, including pesticides, herbicides, and industrial chemicals. They can also be produced by certain bacteria and fungi.

Exposure to these agents can cause a variety of health problems, including death. It is important to be aware of the dangers of these agents and to take steps to avoid exposure.

Therefore, the answer is an agent that binds to pyruvate and inactivates it.

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