Discuss potential advantages and disadvantages of using water as a solvent in organic chemistry.
Question: Discuss potential advantages and disadvantages of using water as a solvent in organic chemistry.
Water is a common solvent in organic chemistry, but it has both advantages and disadvantages. Some of the advantages are:
- Water is cheap, abundant, and environmentally friendly.
- Water can dissolve many polar and ionic compounds, such as alcohols, carboxylic acids, amines, and salts.
- Water can act as a nucleophile, a base, or an acid in some reactions, such as hydrolysis, hydration, and deprotonation.
- Water can form hydrogen bonds with organic molecules, which can stabilize transition states and intermediates.
Some of the disadvantages are:
- Water is not compatible with many non-polar compounds, such as alkanes, ethers, and aromatics.
- Water can react with some functional groups, such as aldehydes, ketones, and esters, and cause unwanted side reactions or hydrolysis.
- Water can promote hydrolysis of some reagents, such as acid chlorides, anhydrides, and halides.
- Water can lower the yield and purity of some reactions by forming emulsions or precipitates.
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