Where in the cell does cellular respiration take place?

Question: Where in the cell does cellular respiration take place?

Cellular respiration, a vital metabolic process that occurs in cells, involves several stages each taking place in specific locations within the cell. Initially, glycolysis occurs in the cytoplasm, where glucose is broken down into pyruvate, yielding energy in the form of ATP. The pyruvate then enters the mitochondria, where it undergoes oxidation to form acetyl CoA. This step marks the transition to the Krebs cycle, which takes place in the mitochondrial matrix. Here, acetyl CoA is further processed to produce ATP, NADH, and FADH2. The final stage, oxidative phosphorylation, occurs across the inner mitochondrial membrane where the electron transport chain is located. This stage harnesses the energy from electrons transferred through various proteins to generate a significant amount of ATP. In the absence of oxygen, cells can resort to fermentation in the cytoplasm to produce ATP.

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